Basic infomation |
source |
Mouse |
Clonality |
Polyclonal |
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Isotype |
IgG |
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Reactivity |
H M R |
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MW (kDa) |
22kDa |
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Purification |
Antigen affinity purfication |
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UniProt ID |
P01116 |
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NCBI Gene |
3845 |
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Applications |
Tested Applications |
WB, |
Cited Applications |
WB, IHC, IF |
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Product Usage Information |
Western Blotting |
1:1000-1:2000 |
Immunohistochemistry |
1:200-1:400 |
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Immunofluorescence |
1:200-1:400 |
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Storage |
PBS with 50% glycerol and less than 0.02% sodium azide |
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Store at –20°C, stable for one year after shipment |
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Do not aliquot the antibody |
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Background |
This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. |
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Abbreviation |
H: human M: mouse R: rat Rb: rabbit Hm: hamster Mk: monkey Vir: virus C: chicken Z: zebrafish Dg: dog Pg: pig Hr: horse |