当前位置:首页  >  产品展示  >  抗体  >  一抗

CCND1 antibody

Catalog Number:PP1265

发布时间:2024-10-15 浏览量:71
订购热线:0551-66199177
说明书:说明书
价格:

Basic infomation

source

Mouse

Clonality

Polyclonal

Isotype

IgG

Reactivity

H M R

MW (kDa)

34kDa

Purification

Antigen affinity purfication

UniProt ID

P24385

NCBI Gene

595

 

 

Applications

Tested Applications

WB,

Cited Applications

WB, IHC, IF

Product Usage

Information

Western Blotting

1:500-1:2000

Immunohistochemistry

1:200-1:400

Immunofluorescence

1:200-1:400

 

 

Storage

PBS with 50% glycerol and less than 0.02% sodium azide

Store at –20°C, stable for one year after shipment

Do not aliquot the antibody

Background

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of human cancers.

 

 

Abbreviation

H: human M: mouse R: rat Rb: rabbit Hm: hamster Mk: monkey Vir: virus C: chicken  Z: zebrafish Dg: dog Pg: pig Hr: horse 

返回列表
  上一篇:CCND3 antibody
下一篇:CCNC antibody  
Copyright © 安徽普尔生物科技有限公司 All Rights Reserved.   皖ICP备2023013304号-1