当前位置:首页  >  产品展示  >  抗体  >  一抗

IDE antibody

Catalog Number:PP1121

发布时间:2024-10-16 浏览量:73
订购热线:0551-66199177
说明书:说明书
价格:

Basic infomation

source

Mouse

Clonality

Polyclonal

Isotype

IgG

Reactivity

H M R

MW (kDa)

118kDa

Purification

Antigen affinity purfication

UniProt ID

P14735

NCBI Gene

3416

 

 

Applications

Tested Applications

WB,

Cited Applications

WB, IHC, IF

Product Usage

Information

Western Blotting

1:500-1:2000

Immunohistochemistry

1:200-1:400

Immunofluorescence

1:200-1:400

 

 

Storage

PBS with 50% glycerol and less than 0.02% sodium azide

Store at –20°C, stable for one year after shipment

Do not aliquot the antibody

Background

This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but have not been experimentally verified.

 

 

Abbreviation

H: human M: mouse R: rat Rb: rabbit Hm: hamster Mk: monkey Vir: virus C: chicken  Z: zebrafish Dg: dog Pg: pig Hr: horse 

返回列表
  上一篇:IKKß (IKBKB) antibody
下一篇:HMGB4 antibody  
Copyright © 安徽普尔生物科技有限公司 All Rights Reserved.   皖ICP备2023013304号-1