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ACTR1A antibody

Catalog Number:PP1619

发布时间:2025-04-30 浏览量:27
订购热线:0551-66199177
说明书:说明书
价格:

Basic infomation

source

Mouse

Clonality

Polyclonal

Isotype

IgG

Reactivity

H M R

MW (kDa)

42kDa

Purification

Antigen affinity purfication

UniProt ID

P61163

NCBI Gene

10121

 

 

Applications

Tested Applications

WB,

Cited Applications

WB, IHC, IF

Product Usage

Information

Western Blotting

1:1000-1:2000

Immunohistochemistry

1:200-1:400

Immunofluorescence

1:200-1:400

 

 

Storage

PBS with 50% glycerol and less than 0.02% sodium azide

Store at –20°C, stable for one year after shipment

Do not aliquot the antibody

 

Background

This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin. 

 

 

Abbreviation

H: human M: mouse R: rat Rb: rabbit Hm: hamster Mk: monkey Vir: virus C: chicken  Z: zebrafish Dg: dog Pg: pig Hr: horse 

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