Basic infomation

source

Mouse

Clonality

Polyclonal

Isotype

IgG

Reactivity

H M R

MW (kDa)

50kDa

Purification

Antigen affinity purfication

UniProt ID

P14136

NCBI Gene

2670

Applications

Tested Applications

WB,

Cited Applications

WB, IHC, IF

Product Usage

Information

Western Blotting

1:3000-1:5000

Immunohistochemistry

1:400-1:800

Immunofluorescence

1:400-1:800

Storage

PBS with 50% glycerol and less than 0.02% sodium azide

Store at –20°C, stable for one year after shipment

Do not aliquot the antibody

Background

This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Abbreviation

H: human M: mouse R: rat Rb: rabbit Hm: hamster Mk: monkey Vir: virus C: chicken  Z: zebrafish Dg: dog Pg: pig Hr: horse